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3 (100), 2021


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Edition of the journal is supported partially by the grant of the Fogarty International Center (FIC) of the National Institute of Health and Illinois University, Chicago.

JOURNAL

ISSN 2077-7477 (Print)
ISSN 2077-7485 (Online)

A journal "Dovkillia ta zdorovia" (Environment & Health) publishes the articles on the problems in the field of medical ecology, hygiene, health protection and ecological safety.

Founder of the Journal:
State Institution "O.M. Marzeiev Institute for Hygiene and Medical Ecology of the National Academy of Medical Sciences of Ukraine"

Frequency of publication:
quarterly

Environment & HealthISSN: 2077-7477 eISSN: 2077-7485
No: 3 (100)   -   September, 2021   -   Pages: 38-43
To the issue of the probable role of plant protection chemicals in the formation of population oncological incidence
Chernychenko I.O.1, Lytvychenko O.M.1, Babii V.F.1, Fedorenko Z.P.2, Tsymbaliuk S.M.3, Balenko N.V.1, Kondratenko O.Ye.1, Hlavachek D.O.1
1 State Institution "O.M. Marzeiev Institute for Public Health of the NAMSU"
2 National Cancer Institute of MHU
3 Kyiv City Clinical Endocrinology Center of MHU

: 614.777:546.79:628.16

ABSTRACT:
Objective: We assessed a probable role of pesticides as generalized products of plant protection means in the formation of the hormone-dependent oncological incidence in the population.

Materials and methods: In the work we analyzed the territorial features of plant protection chemicals use and the population endocrine cancer incidence data (breast and thyroid cancer in men and women, prostate cancer in men, ovarian and uterine cancer in women, calculated according to the Ukrainian standard) based on the materials from National Cancer Registry of Ukraine.

Results: Territorial dependences between gross indicators of the used chemical protection means, rates of their increase in the agriculture and indicators of the population endocrine cancer incidence were revealed. The most intensive growth was shown to be observed in the regions with a predominantly agricultural mode of production. The performed linear regression analysis confirmed a direct strong correlation between the volume of pesticide at the household use and the incidence of ovarian cancer (r = 0.89; p>0.01) and prostate cancer (r = 0.87; p>0.01).

Conclusion: Although the results of the analytical consideration of the problem and the data of linear-regression analysis indicate a possible role of pesticides in the induction of endocrine cancer, further research is needed in this field. In the future, it is important to consider the problem by classes and groups of pesticides with the possibility of the approach to the definition of the effect mechanisms.

KEYWORDS:
plant protection chemicals, oncological incidence of the population, territorial features
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