| Environment & Health | ISSN: 2077-7477 eISSN: 2077-7485 |
No: 1 (81) - 2017 - Pages: 65-72
For the question of xenobiotics biological monitoring
Kudria M.Ya.1, Lalymenko O.S.1, Karachentsev Yu.I.1, Zavhorodny I.V.2
1 SI “V.Ya. Danylevskyi Institute of Endocrinological Pathology Problems, NAMSU”, Kharkiv
2 Kharkiv National Medical University, Kharkiv
ÓÄÊ: 613.63 : 615.9 : 615.252.349.7
SUMMÀRY:
This article provides information and contemplations of the authors about the problem of biological monitoring of hazardous chemicals and its introduction into the practice of occupational hygiene and environmental protection. We have analyzed the scientific findings of international normative and legal documents concerning the risk assessment of the exogenic chemical compounds effect on the state of health of the employees and the population using the comprehensive approaches of biomonitoring methodology. The authors invite to discuss a definition of "biological maximum allowable concentration - bio MAC" in the context of the hygienic regulations among the researchers in the occupational hygiene. We substantiate the urgency and the practical necessity of the introduction of biological monitoring in risk assessment of the effect of hazardous chemical factors on the health of the employees and the population.
KEYWORDS:
biological monitoring, risk assessment of chemical exposure, biomarkers
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