|Environment & Health||ISSN: 2077-7477 eISSN: 2077-7485
No: 2 (87) - June, 2018 - Pages: 23-28
Investigations of genotoxicity of low-frequency electromagnetic fields. Current state (second report)
Balenko N.V.1, Sovertkova L.S.1, Chernichenko I.O.1, Babii V.F.1, Dumanskyi Yu.D.1, Lytvychenko O.M.1, SerdiukYe.A.1, KondratenkoO.Ye.1
1 State Institution "O.M. Marz³eiev Institute for Public Health of the NAMSU"
ÓÄÊ: 537.531 : 613.648.2 : 547.414 : 576.385.5
Objective: We analyzed the current state of the issue of the investigations on the genotoxicity of low-frequency electromagnetic fields (LFEMF).
Material and methods: We analyzed the literary findings on the study of cytogenetic damages in humans exposed to LF EMF.
Results: The investigations of genotoxic effects were established to be concerned with the occupationally exposed individuals as long as such investigations in the population were practically absent. Genotoxicity was assessed by means of the detection of DNA damages (Comet-test), chromosomal aberrations and micronuclei formation in lymphocytes and buccal cells. The results, obtained by the authors, were unequal and sometimes contradictory. These differences may be partially explained by various levels and duration of LF EMF effect and a number of the admitted shortcomings affecting the results. Nevertheless, on the whole, the human cytogenetic biomonitoring investigations in humans showed positive results that allowed to suppose the genotoxicity of LF EMF. A dose-time dependence of genotoxic effects in humans exposed to LFELF is shown in the isolated works. The problems, concerning minimum effective and maximum non-effective levels, are still unsolved.
Conclusions: Literary findings confirm the necessity of further investigations in this direction among occupational exposed humans and population to solve the number of problems connected with the hazard evaluation of various LF EMF levels for the development of the effective protective measures from their harmful influence on human health in the occupational and environmental conditions.
low-frequency electromagnetic fields, exposed humans, genotoxic damages, lymphocytes, buccal cells
1. JARC Monographs on the Evaluation of Carcinogenic Risk to Humans. Non-ionizing Radiation, Part 2: Radiofrequency Electromagnetic Fields. Lyon : JARC ; 2013 ; 102 ; 429 p.
3. Bonassi S., Hagmar L., Stromberg U., Tinnerberg H. et al. Cancer. Res. 2000 ; 60 :1619-1625.
13. Erdal M.E., Erdal N. and Oguskan S. Turk J. Med. Sci. 1999 ; 29 : 335-336.
27. Villarini M., Dominici L., Fatigoni C., Levorato S. et al. Ann. Ig. 2015 ; 27 : 511-519.
29. Gobba F., Rocatto L., Sinigaglia B. and Temperani P. Med. Lav. 2003 ; 94 : 450-458.
30. Scearingi M., Temperani P., Rossi P., Bravo G. and Gobba F. Giorn. It. Med. Lavoro Ergon. 2007 ; 29 : 420-421.
32. Verschaeve L., Juutilainen J., Lagroye I. et al. Mut. Res. 2010 ; 70 S : 252-268.
34. Environmental Health Criteria 238: Extremely Low Frequency Fields. Geneva : WHO ; 2007 : 100 p.