The results of the scientific research of the features of diabetes mellitus impact on the occurrence of parodontitis among people aged 18 - 24 years are represented in the article. Diabetes melliyus is one of the main risk factors affecting the occurrence of parodontitis. Parodont diseases are one of the main causes of premature tooth loss, which leads to the deformities and a decrease in the functionality of the maxillodental system, a decrease in the volume of bone tissue, which complicates the complex orthopedic rehabilitation of the patients.

Objective: We analyzed the features of diabetes impact on parodontitis development among people aged 18 to 24 years while using the methods of complex hygienic and clinical-laboratory diagnostics for the prevention of disorders of osteointegration processes.

Materials and methods: The study was conducted among the residents of Uzhgorod city aged 18 to 24 years on the basis of the University Dental Clinic and private dental clinics. 387 patients were examined during 2016-2020. In the study, we used hygienic and clinical-and-laboratory diagnostic methods. We examined people with diabetes of type I and type II and diagnosed parodontitis.

Results and discussion: The results of mathematical-and-statistical analysis confirm the impact of diabetes mellitus on the development of parodontitis in people aged 8-24 years among examined population.

Conclusions: It was established that the manifestations of parodontitis depend more on the severity of diabetes mellitus than on its duration (r=0.74, tST=2.5413, F= 2.59441 while Fcrit= 2.447). The negative impact of diabetes mellitus on the condition of the maxillary tissue also has been determined (bone resorption - r = 0.87, tST = 2.75257, F = 5.582 at Fcrit = 2.447).

diabetes mellitus, periodontitis, age group 18-24 years, hygienic diagnostics, clinical and laboratory diagnostics

1. 1.Fera M.O., Fera O.V., Kryvanych V.M., Kostenko S.B., Keniuk A.T., Starenkyi A.R. et al. Doslidzhennia vplyvu faktoriv ryzyku (tsukrovyi diabet, zbalansovanist rezhymu kharchuvannia, hihiiena rotovoi porozhnyny) na vynyknennia heneralizovanoho parodontytu v osib vikom 45–55 rokiv sered naselennia m. Uzhhorod ta Uzhhorodskoho raionu [The Research of the Influence of the Risk Factors (Diabetes Mellitus, Balanced Diet Mode, Oral Hygiene) on the Occurrence of Generalized Periodontitis in People Aged from 45 to 55 Years Among the Population of Uzhgorod and Uzhgorod District]. Problemy klinichnoi pediatrii. 2020 ; 4 : 25-33 (in Ukrainian).

2. Fera M.O., Fera O.V., Kryvanych V.M., Bilyschuk L.M., Kostenko S.B., Kryvanych A.V. et al. Analysis of Environmental and Person-Oriented Factors Influenceon Dental Caries Intensity among Children Population of Transcarpathia. Journal of International Dental and Medical Research. 2020 ; 13(14) : 1326-1333.

3. Fera O.V., Kostenko E., Fera M.O., Dyachuk K.G., Kukharchuk L.V., Kohut E.G. et al. Osoblyvosti zviazkiv faktoriv dovkillia iz zakhvoriuvanistiu na pulpit v osib vikom vid 15 do 17 rokiv sered naselennia m. Uzhhorod ta Uzhhorodskoho raionu [Features of Relations Between Environmental Factors and Pulpitis Rate in Persons Aged 15 to 17 Years Among the Population of Uzhgorod Uzhgorod District]. Problemy klinichnoi pediatrii. 2017 ; 1-2 :103-108 (in Ukrainian).

4. Fera M.O., Fera O.V., Kryvanych V.M., Foros A.I., Kukharchuk L.V. Osoblyvosti vplyvu sotsialno-hihiienichnykh faktoriv na formuvannia stomatolohichnoi zakhvoriuvanosti orhaniv rotovoi porozhnyny u zhyteliv nyzynnoi zony Zakarpattia [Features of the Effect of Social-Hygienic Factors on the Formation of the Dental Disease in the Oral Cavity in the Residents of the Lower Zone of Transcarpathia]. Problemy klinichnoi pediatrii. 2019 ; 2 (44) : C. 6-12 (in Ukrainian).

5. Fera O., Kostenko Ye., Fera M., Krivanich V., Kukharchuk L., Kohut E., Penzelik I. et al. Vzaiemozviazok osoblyvostei ta rezhymu kharchuvannia, sposobu zhyttia, chynnykiv dovkillia iz zakhvoriuvanistiu na pulpit u pidlitkiv 15-17 rokiv v Uzhhorodi ta Uzhhorodskomu raioni [Features and Interaction Mode Diet, Lifestyle, Environmental Factors with the Incidence of Pulpitis in Adolescents Aged 15-17 Years in Uzhgorod and Uzhgorod District]. Problemy kharchuvannia [One health and nutritions problems of Ukraine]. 2016 ; 2 : 58–68 (in Ukrainian).

6. Fera O., Kostenko Ye., Fera M., Kryvanych V., Dyachuk K., Negrya A. et al. Osoblyvosti vplyvu kharchuvannia ta inshykh faktoriv pobutu i dovkillia na vynyknennia ta rozpovsiudzhennia periodontytu sered osib vikom vid 24–29 rokiv m. Uzhhorod ta Uzhhorodskoho raionu [Features of Nutrition and other Factors of Life and Environment Influence on the Emergence and Spreading of Periodontitis among 24-29 Year Old Population of Uzhhorod City and Uzhhorod Region]. Problemy kharchuvannia [One Health and Nutritions Problems of Ukraine]. 2017 ; 1 : 10-16 (in Ukrainian).

7. Serdiuk A.M., Bazyka D.A., Tronko M.D. (Eds.). Natsionalnyi ohliad «Endokrynni ruinivnyky v Ukraini: stan problemy ta shliakhy yii vyrishennia» [National Review "Endocrine Disruptors in Ukraine: the State of the Problem and Ways to Solve It"]. Kyiv ; 2018 : 169 p. (in Ukrainian).

8. Yeltsova L.B. and Omelchuk S.T. Obhruntuvannia shliakhiv udoskonalennia anketno-opytuvalnoho metodu otsinky faktychnoho kharchuvannia naselennia [Substantiatin of Ways for Improvement of Questionare-Survey Method of Assessment of Population`s Actual Nutrition]. Medychni perspektyvy. 2017 ; XXII (3) : 104-112 (in Ukrainian). DOI : https://doi.org/10.26641/2307-0404.2017.3.111935

9. Nazarenko Z.Yu. Suchasnyi stan pytannia likuvannia khronichnoho heneralizovanoho parodontytu u khvorykh na foni tsukrovoho diabetu [Present-Day Aspects of Chronic Generalised Parodontitis Therapy in Patients with Diabetes Mellitus]. Aktualni problemy suchasnoi medytsyny: Visnyk Ukrainskoi medychnoi stomatolohichnoi akademii. 2006 ; 6 : 3-15 (in Ukrainian).

10. Bilko T.M. and Omelchuk S.T. Vplyv alimentarnoho defitsytu zhyrorozchynnykh vitaminiv na endokrynnyi status divchat-pidlitkiv [Impact of Alimentary Deficiency of Fat-Soluble Vitamins on the Endocrine Status of Adolescent Girls]. Obstetrics. Gynecology. Genetics. 2015 ; 2 : 5-11 (in Ukrainian).

11. Dereiko L.V. and Plieshakova V.V. Vzaiemozviazok mizh parodontytom i zahalnym stanom zdorovia [Relationship Between Parodontitis and General State of Health]. Implantolohiia Parodontolohiia Osteolohiia. 2011 ; 2 : 76-84 (in Ukrainian).

12. Nikitin V., Kapitonova O. and Antonova I. Osobenosti dentalnoy implantatsii u patsientov s sakharnym diabetom. [Dental Implant Treatment Features in Patients with Diabetes Mellitus]. Translyatsionnaya meditsina. 2015 ; 2(6) : 25-31 (in Russian).

13. Bardov V.H. and Omelchuk S.T. Hihiiena ta ekolohiia : pidruchnyk [Hygiene and Ecology: Textbook]. Vinnytsia : Nova Knyha ; 2020 : 472 p. (in Ukrainian).

14. Serdiuk A.M., Hulich M.P., Petrenko O.D., Liubarska L.S. and Koblianska A.V. Otsinka obiznanosti ta usvidomlennia studentskoiu moloddiu roli kharchuvannia u rozvytku neinfektsiinykh zakhvoriuvan [Assessing the Awareness and Consciousness of Young Students about the Role of Nutrition in the Development of Non-Infectious Diseases]. Dovkillia ta zdorovia (Environment&Health). 2019 ; 2 (91) : 27-31 (in Ukrainian).

15. Yavorovskyi O.P. Narysy z toksykolohii vazhkykh metaliv (Retsenziia na tsykl naukovykh vydan «Narysy z toksykolohii vazhkykh metaliv: I – Svynets; II – Rtut; III – Kadmii; IV – Marhanets, Khrom; V – Zalizo» za zahalnoi redaktsii akademika NAMN Ukrainy, chlena-korespondenta NAN Ukrainy I.M. Trakhtenberha, Kyiv : Avitsenna) [Review of a Series of Scientific Publications "Essays on Toxicology of Heavy Metals: I - Lead; II - Mercury; III - Cadmium, IV - Manganese, Chromium; V - Iron »]. Dovkillia ta zdorovia (Environment&Health). 2019 ; 4 : 66-69 (in Ukrainian).