|Environment & Health||ISSN: 2077-7477 eISSN: 2077-7485
No: 4 (101) - December, 2021 - Pages: 11-18
Homocysteine, pituitary and thyroid hormones in children with different physical growth levels after forest fires in the Chernobyl exclusion zone
Bandazhevskyi Yu. I.1, Dubova N. F.2
1 Ecology and Health Coordination and Analytical Centre, Ivankov
2 Shupyk National Healthcare University of Ukraine
Objective We performed a comparative assessment of the blood levels of homocysteine, pituitary and thyroid hormones in children with different levels of physical development before and after forest fires in the Chornobyl exclusion zone (ChEZ) in 2015.
Methods: We used immunochemical, instrumental, mathematical and statistical methods.
Results: The analysis of variable dynamics was performed in 336 adolescents of the Polisskyi and the Ivankivskyi districts of Kyiv region. An association was found between homocysteine (Íñó), hormones of the pituitary-thyroid axis and physical development of children. A statistically significantly higher level of Íñó was observed in the adolescents from the Ivankivskyi district in comparison with the children from the Polisskyi district. Forest fires in the spring and summer of 2015 in the ChEZ should be considered the main cause for the increase in Íñó in the blood of the adolescents. The increased level of Ò3 in the peripheral tissues induced by Íñy and TSH contributed to a decrease in the physical development index values. Due to a decrease in the intensity of the Ò4 deiodination process, the insufficient formation of Ò3 in the peripheral tissues was recorded in the group of children with a disharmonious high physical development.
homocysteine, hypophysis and thyroid gland hormones, physical development , adolescents, forest fires, Chornobyl exclusion zone.
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