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Edition of the journal is supported partially by the grant of the Fogarty International Center (FIC) of the National Institute of Health and Illinois University, Chicago.

JOURNAL

ISSN 2077-7477 (Print)
ISSN 2077-7485 (Online)

A journal "Dovkillia ta zdorovia" (Environment & Health) publishes the articles on the problems in the field of medical ecology, hygiene, health protection and ecological safety.

Founder of the Journal:
State Institution "O.M. Marzeiev Institute for Hygiene and Medical Ecology of the National Academy of Medical Sciences of Ukraine"

Frequency of publication:
quarterly

Environment & HealthISSN: 2077-7477 eISSN: 2077-7485
No: 3 (79)   -   2016   -   Pages: 10-14
The hepatoprotective role of the Zakarpattia herbal preparations in experimental atherosclerosis and diabetes mellitus type 2
Biloshytska A.V.1
1 M.I. Pyrogov National Medical University, Vinnytsia

: 616.36 007: 616.379 008 64: 616.13 004.6 - 084

ABSTRACT:
Background. Today atherosclerosis and type 2 diabetes mellitus are the most socially significant diseases. The situation is aggravated by chronic stress experienced by the Ukrainian people. There is a liver among target organs which are affected primarily.

Objective. We studied the structural reconstruction of the liver tissue during the experimental atherosclerosis and diabetes mellitus and at its prophylaxis with herbal preparations.

Materials and methods. The study was performed on 50 male rats. We used the classical model of atherosclerosis by N. Anichkov and dexamethasone suppression model of diabetes mellitus. We
used a decoction of the Zakarpattia medicinal plants (by our recipe) as a prophylactic agent.

Results. Experimental model of atherosclerosis and diabetes mellitus showed that degenerative changes had been developed in the liver. These changes are the most pronounced in the group with the concurrent simulation of pathologies. Prophylactic administration of traditional medicinal plants of Zakarpattia had pronounced hepatoprotective effect.
Conclusions. Experimental atherosclerosis and diabetes mellitus lead to the degenerative changes in the liver parenchyma and stroma. Prophylactic administration of decoction of medicinal plants of Zakarpattia has hepatoprotective effect confirmed by the morphological studies.

KEYWORDS:
atherosclerosis, type 2 diabetes mellitus, liver, phytoprophylaxis.
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