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2 (103), 2022


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Edition of the journal is supported partially by the grant of the Fogarty International Center (FIC) of the National Institute of Health and Illinois University, Chicago.

JOURNAL

ISSN 2077-7477 (Print)
ISSN 2077-7485 (Online)

A journal "Dovkillia ta zdorovia" (Environment & Health) publishes the articles on the problems in the field of medical ecology, hygiene, health protection and ecological safety.

Founder of the Journal:
State Institution "O.M. Marzeiev Institute for Hygiene and Medical Ecology of the National Academy of Medical Sciences of Ukraine"

Frequency of publication:
quarterly

Environment & HealthISSN: 2077-7477 eISSN: 2077-7485
No: 2 (103)   -   June, 2022   -   Pages: 16-24
Cancer incidence in the population of Ukraine in remote period after the Chornobyl accident
Prysyazhniuk A.Ye.1, Bazyka D.A.1, Hudzenko N.A.1, Fuzik M.M.1, Trotsiuk N.K.1, Babkina N.G.1, Khukhrianska O.M.1, Danevych S.A.1
1 SI National Research Centre for Radiation Medicine of National Academy of Medical Sciences of Ukraine, Kyiv

: 616-006:616-001.28:614-876:616-036.22

ABSTRACT:
There is performed a study of cancer incidence in the population affected by the Chornobyl accident. Analysis of demography situation has shown that unlike Western European countries with increasing life expectancy this index was notably decreased in Ukraine in 20052006 with slow growth during 20062019. Certainly this circumstance may influence on cancer incidence rate because the highest risk of malignant tumours is just in elderly age.

Goal: to determine the frequency and risk of malignant neoplasms in groups of the population of Ukraine that were exposed to radiation as a result of the Chrnobyl accident in the remote post-accident period.

Materials and methods. The study was conducted on the basis of long-term monitoring of malignant tumours in the groups of victims clean-up workers of 19861987, evacuees from the exclusion zone, residents of the territories most heavily contaminated with radionuclides.

Results. There was a significant excess of the expected level of incidence of thyroid cancer among the participants in liquidation of the accident consequences (PLAC) - 4.5 times, evacuees - 3.8 times, residents of territories contaminated with radionuclides - 1.3 times.
Leukaemia and lymphoma incidence rate in residents of contaminated territories increased sharply in the first years after the accident but decreased in the next years and not exceeded the level if Kyiv and Zhytomyr regions and Ukraine at whole.
In a joint Ukrainian-American analytical epidemiological case-control study dose dependent excess relative risk of leukaemia (ERR/Gy) was proved in clean-up workers and defined at level 2.38 (0.495.87) in 19862006.
A significant excess of the national level of incidence of breast cancer was determined only in women - PLAC in 19861987. In 19942019 SIR was 156.3% (95% CI: 141.0171.5).

Conclusions. Because latency period for different forms of radiation related malignancies might be very long further special attention should be paid not only to nosological forms mentioned above but also to cancers of the other sites.

KEYWORDS:
ionizing irradiation, Chornobyl accident, malignant tumours, affected population
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